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NEXIUM had no effect on thyroid function when given in oral doses of 20 or 40 mg for 4 weeks.

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Although small observational studies had demonstrated a small benefit in 5-year mortality and a decrease in development of visceral disease, the role of d-penicillamine remains unclear.

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In a large cohort of patients in metropolitan Detroit, the poor prognostic markers were found to be older age at onset, male gender, African American race, and involvement of certain organ systems (heart, interstitial lung disease, pulmonary hypertension, and severe gastrointestinal disease).

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H2 blockers are also available over the counter under such generic names as famotidine (Pepcid), cimetidine (Tagamet) and ranitidine (Zantac).

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An increased incidence of treatment-related ECL cell hyperplasia was observed at the end of 1 year (94% treated vs 10% controls).

The prognosis depends on the category of disease as well as on the condition of the patient when the infection strikes.

HMS links the severe and sometimes fatal diarrhea caused by the bacterium Clostridium difficile to long-term PPI use, which contributes to bacterial overgrowth.

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The safety and effectiveness of generic drugs are established by the fact that all of them go through the FDA review and approval procedure.

This is the final step in gastric acid production, and by blocking the final step in the production process, Nexium is able to reduce gastric acid by up to 99%.

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